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Global Registration Identifier for Donors

ST-015 Standard Global Registration Identifier for Donors: ION Database and GRID Rules v3.2.0 – PDF. The purpose of this document is to provide: specifications for the structure of the Global Registration Identifier for Donors (GRID) and the Issuing Organization Number (ION). The ION Grid is a Java-based application server that provides a distributed runtime environment for other applications. Those other applications may, at any time, be added (deployed) or removed (undeployed) from a grid. The distributed nature of a grid means that an instance of the Infor ION Grid may span multiple server machines. Global Registration Identifier for Donors. With over 39 million donors worldwide, it is important to have a system that uniquely identifies potential donors on a global scale.

With over 39 million donors worldwide, it is important to have a system that uniquely identifies potential donors on a global scale. This helps to:

  • reduce the risk of misidentification of donors or their donations due to the lack of global uniqueness of identifiers;
  • provide a standard machine-readable format (barcodes) that can be used by computer systems; and
  • define a standard presentation for the human-readable identifier.

To this end, WMDA has developed a unique global donor identifier to ensure secure, reliable and unambiguous assignment of donors: the Global Registration Identifier for Donors (GRID).

The purpose of the GRID is to:

  1. Reduce the risk of misidentification of hematopoietic stem cell donors, due to the lack of global uniqueness of identifiers;
  2. Provide a standard eye-readable format for the donor identifier that can be used by humans;
  3. Provide a standard machine-readable format for the donor identifier that can be used by computer systems;
  4. Provide a check sum for transcription control;
  5. Provide consistent documentation;
  6. Improve traceability of donors.
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All organisations involved in the process of recruiting, facilitating and providing haematopoietic stem cells from volunteer donors have implemented or are in the process of implementing GRID. Established systems such as ISBT-128 or Single European code (SEC), which standardize the terminology, identification, coding and labelling of medical products of human origin, serve as the basis for GRID.

WMDA has established a partnership with the International Council for Commonality in Blood Bank Automation (ICCBBA) to manage and maintain the GRID.

From 15th December 2020 GRID must be fully implemented for all organisations and will be the only donor identifier to be shown in the search & Match Service. Final references to the old donor ID will no longer be visible within the Search & Match Service and should be discontinued. WMDA acknowledges that on a registry level, the current donor IDs will never fully be removed and must be maintained for historical traceability and quality. The expectation is that use of these IDs in daily processes and communications (technical and operational) are discontinued. Continued use of multiple IDs is inherently a risk of misidentification and miscommunication.

Quick links:

What is GRID?

  • Publication explaining GRID: Global Registration Identifier for Donors (GRID) of Hematopoietic Stem Cells: Road to Automation and Safety

Technical details about GRID:

  • Technical documentation: ION database and GRID rules
  • Technical documentation: Technical Specification

Operational tools:

Implementation documents:

Implement GRID in your registry

  • Template: Global Registration Identifier for Donors (GRID) – implementation plan

GRID has improved electronic communication, traceability, and accuracyin unambiguously identifying potential donors by standardizing systems of donor identification across the globe.

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Ultimate flexibility

1 - 5 flow cells

Run multiple DNA/RNA sequencing experiments

Up to 250 Gb*

High-throughput data generation

* Theoretical max output when system is run for 72 hours at 420 bases / second. Outputs may vary according to library type, run conditions, etc.

Why GridION?

Flexible

Run up to five independently addressable Flongle or MinION Flow Cells.

High throughput

As much as 250 Gb of data* — streamed in real time for immediate analysis.

* Theoretical max output when system is run for 72 hours at 420 bases / second. Outputs may vary according to library type, run conditions, etc.

Integrated compute

Powerful onboard data processing and analysis, minimising IT requirements.

No capital cost

Pay just for consumables.

Service provider certification is available for GridION

Assembly-free viral genomes from environmental samples

Find out how long nanopore sequencing reads enabled the recovery of 1,863 full-length viral genomes from sea water samples.

Understanding the genomes of endangered animal species

Discover how the high-throughput GridION supported the generation of a highly complete genome for the endangered red-spotted grouper Epinephelus akaara.

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Specifications

Read length

Nanopores read the length of DNA or RNA presented to them — from short to ultra-long (longest >4 Mb)

Dimensions

Compact benchtop device with integrated compute suitable for any lab

  • Size: W 370 mm, H 220 mm, D 365 mm
  • Weight: 11 kg

250 Gb yield*

Up to 50 Gb per MinION Flow Cell / 2.8 Gb per Flongle Flow Cell*

* Theoretical max output when system is run for 72 hours (or 16 hours for Flongle) at 420 bases / second. Outputs may vary according to library type, run conditions, etc.

Suitable applications

  • Larger genomes or projects
  • Whole transcriptomes (direct RNA or cDNA)
  • Large numbers of samples

On demand

Sequence what you need, when you need it

  • Run flow cells individually or together — no more sample batching
  • Mix MinION and Flongle Flow Cells to suit experimental needs
  • Run multiple DNA or RNA experiments at once
  • Barcode for even more samples

Accessible

  • No capital cost
  • Simple plug and play operation
  • Integrated compute — minimal IT infrastructure required

Powerful, integrated compute

Sequencing and analysis in one powerful device

  • Latest generation CPU / GV100 GPU accelerator
  • 64 GB RAM / 4 TB SSD storage
  • Ethernet connectivity
  • Instrument control and data analysis software

Product documentation

GridION Mk1 Quick Start Guide

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Everything you need to install your GridION Mk1 and to check the system is ready for use.

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GridION Mk1 device specs

GridION Mk1 Technical Specification

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GridION Mk1 IT requirements

This checklist represents the minimal requirements for installing the GridION.

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Safety and regulatory information

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